Sociodemographic Factors Affect Oral Cancer Screenings

When oral cancers are discovered in the early stage, the survival rate is 82.8% versus 28% when the disease is found after metastasis; therefore, it is important to implement preventive measures for early diagnosis of oral cancer. Researchers evaluated rates of oral cancer among those who have been to the dentist in the past two years to determine if sociodemographic factors, like income or race, predict discrepancies in the rate of diagnosis and found that a significantly high amount of minorit...

Adavosertib (AZD1775) with Gemcitabine and Radiation for Locally Advanced Pancreatic Cancer: An Interview with Kyle C. Cuneo, MD

Pancreatic cancer is one of the most aggressive forms of cancer, and owing to limited treatment options, it has one of the lowest survival rates. While patients are commonly treated with radiation therapy, there is a need to develop alternative treatment options that can improve the efficacy of radiation, reduce tumor progression, and increase survival. In a recent study, Kyle C. Cuneo, MD, and colleagues evaluated the safety and tolerability of adavosertib (AZD1775), an inhibitor of the Wee1 ki...

Biomarkers in Liquid Biopsies Detect Glioblastoma Tumors

Researchers have identified glioblastoma biomarkers in extracellular vesicles that could enable a liquid biopsy, serving as a more efficient and less invasive means of detecting and subtyping this cancer. The most aggressive type of brain tumor, glioblastoma has a poor survival rate and limited treatment options. While it can currently be diagnosed through tumor biopsies, this method can be time consuming, invasive, and painful. There is a need to develop more effective options for detecting gli...

Knowledge Gaps in the Treatment of Carcinoid Syndrome

Optimal management of carcinoid syndrome in patients with neuroendocrine tumors poses a challenge, due to the fact that the primary symptoms of carcinoid syndrome are associated with more common diseases. Because timely recognition is difficult, symptoms of carcinoid syndrome can negatively impact patients' quality of life and functioning. Baseline data collected from a continuing nursing education (CNE)-approved Oncology Nursing Strategy Session titled Optimizing Management of Carcinoid Syndrom...

Congenital Heart Disease Linked to Cancer: Interview With Zacharias Mandalenakis, MD, PhD

One of the most common birth defects, congenital heart disease (CHD) is associated with an increased risk of developing cancer. Zacharias Mandalenakis, MD and colleagues conducted a study to further explore the link between CHD and cancer. In this interview with i3 Health, Dr. Mandalenakis provides insights on this link and strategies for mitigating risk. What led you to research this topic? Zacharias Mandalenakis, MD, PhD: I am an adult cardiologist, and I work at the Adult Congenital Heart Ass...

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