Metastatic Colorectal Cancer: Treatment Challenges, Progress, and Advice With Chiara Cremolini, MD

Colorectal cancer is the third leading cause of cancer death and the fourth most common diagnosed cancer in the world. Often, this disease is left undiagnosed until it reaches an advanced stage. Unfortunately, late-stage metastatic colorectal cancer has a poor prognosis with a 5-year survival rate of only 12%. In an interview with i3 Health, Chiara Cremolini, MD, provides insights on the challenges of treating patients with metastatic colorectal cancer, explains how metastatic colorectal cancer ...
Continue reading

FOLFOXIRI Efficacy in Metastatic Colorectal Cancer: Chiara Cremolini, MD

Results of TRIBE2, a phase 3 trial (NCT02339116), show that the triplet treatment FOLFOXIRI (fluorouracil/leucovorin/oxaliplatin/irinotecan) plus bevacizumab is more effective at treating patients with metastatic colorectal cancer than FOLFIRI (irinotecan/leucovorin/fluorouracil) plus bevacizumab. In an interview with i3 Health, Chiara Cremolini, MD, lead researcher of this study, provides insights on the results of this trial as well as how the future of treatment for metastatic colorectal canc...
Continue reading

FOLFOXIRI Combo Effective for Metastatic Colorectal Cancer?

According to the results of TRIBE2, a phase 3 trial (NCT02339116), the triplet treatment FOLFOXIRI (fluorouracil, leucovorin, oxaliplatin, and irinotecan) in combination with bevacizumab has been shown to be more effective in treating patients with metastatic colorectal cancer before and after disease progression compared with sequential administration of chemotherapy doublets plus bevacizumab. Patients aged 18 to 75 years with an Eastern Cooperative Oncology Group (ECOG) performance status of 2...
Continue reading

MRI Plus Standard Biopsy: More Effective in Detecting Prostate Cancer?

Low-grade prostate cancers have a much lower risk of cancer-specific death, while high-grade prostate cancers account for the majority of deaths from prostate cancer; therefore, precise diagnosis is of utmost importance. In order to achieve a high rate of accurate detection of this disease, standard biopsy in conjunction with magnetic resonance imaging (MRI) is necessary. A recent study found that when used together, these two techniques are more effective in targeting and sampling suspicious pr...
Continue reading

Exercise Improves Quality of Life in African American Cancer Survivors

Research has shown exercise is crucial to improve cancer outcomes in survivors. The American Cancer Society (ACS) recommends that cancer survivors should exercise for at least 150 minutes of moderate to vigorous physical activity per week. Unfortunately, many cancer survivors do not meet these recommendations. In particular, preliminary research suggests African American cancer survivors engage in lower levels of physical activity, and they have a higher likelihood of dying from their disease th...
Continue reading

Copyright © 2020 i3 Health. All rights reserved.