According to the results of a recently published study, carcinogenic biomarkers strongly linked to bladder cancer risk are found in the urine samples of electronic cigarette (e-cigarette) users.E-cigarettes contain nicotine, additives, and other chemical solvents that can create numerous toxic compounds when heated. Their popularity has increased dramatically in recent years, especially in the adolescent and young adult population. Between 2017 and 2018, usage increased nearly 80% among high sch...

Upper tract urothelial carcinoma (UTUC) is a rare malignancy with a mortality rate of over 50% for locally advanced disease. However, few clinical trials have been conducted due to its low incidence rate. Nephroureterectomy—a surgical procedure in which the renal pelvis, kidney, ureter, and bladder cuff are removed—is considered the standard treatment approach for patients with UTUC, but little research had been conducted regarding the optimal treatment after surgery. In the phase 3 PO...

In patients with locally advanced upper tract urothelial carcinoma (UTUC), adjuvant platinum-based chemotherapy increases disease-free survival compared with surveillance, according to the results of a phase 3 trial.Due to limited symptoms, the majority of patients with UTUC present with muscle-invasive or locally advanced disease, resulting in a mortality rate of over 50%. Few large clinical trials have been conducted in this space due to the rarity of the disease, and nephroureterectomy—a surg...

An exploratory analysis of data from a phase 3 trial observed a high incidence of venous thromboembolic events (VTEs) in patients with locally advanced resectable esophageal cancer undergoing preoperative chemotherapy and chemoradiotherapy, especially in patients with adenocarcinoma.The occurrence of VTEs, including deep vein thrombosis and pulmonary embolus, can negatively impact the clinical outcomes of patients receiving cancer treatment, reducing quality of life and increasing the risk of mo...

A new study reports that nearly a third of patients with primary brain tumors experience clinically significant body image dissatisfaction, which can negatively impact their quality of life and psychosocial well-being.Body image—a concept consisting of cognitive, emotional, and relational elements derived from one's physical appearance—plays an important role in an individual's self-esteem, relationships, and outlook on life. Due to the physical impacts of treatment, patients with cancer face an...