Breast Cancer and COVID-19: Treatment, Triage, and Prioritization

The American Society of Breast Surgeons has released an executive summary of recommendations for prioritizing, treating, and triaging patients with breast cancer during the COVID-19 pandemic."The COVID-19 pandemic poses unprecedented challenges for patients, clinicians and health care systems," write the authors, led by Jill R. Dietz, MD, FACS, President of the American Society of Breast Surgeons. Written by representatives from multiple cancer care organizations with expertise in the multidisci...
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Breast Cancer: BRCA1/2 Mutations Enhance Chemotherapy’s Efficacy

Carriers of germline variants in the BRCA1 and BRCA2 genes are more likely to experience a pathologic complete response to two different chemotherapy regimens, according to a retrospective study now published in JAMA Oncology.This study was a secondary analysis of data from the GeparOcto multicenter prospective clinical trial, in which 945 women with different subtypes of high-risk, early-stage breast cancer were randomized to receive either sequential intense dose-dense epirubicin/paclitaxel/cy...
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Milk and Breast Cancer Risk: Gary E. Fraser, MBChB, PhD

​United States Dietary Guidelines recommend that adults and children aged 9 or older consume three cups per day of low-fat or fat-free milk and dairy foods, or alternatively, three cups of calcium-fortified soymilk. However, a large observational study recently published in the International Journal of Epidemiology reports that consuming three cups of dairy milk per day is associated with a risk of breast cancer that is increased by as much as 80%, regardless of the fat content of the milk,...
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Neratinib: Progress for HER2-Positive Metastatic Breast Cancer With Adam Brufsky, MD, PhD, FACP

Last week, the FDA added a second approval for neratinib (Nerlynx​®​, Puma Biotechnology, Inc.) in combination with capecitabine for adults with human epidermal growth factor receptor 2 (HER2)-positive advanced breast cancer previously treated with at least two anti-HER2–based regimens in the metastatic setting. This adds to the previous approval of neratinib, an irreversible pan-HER tyrosine kinase inhibitor, for the extended adjuvant treatment of early-stage HER2-positive breast cancer followi...
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Dairy Consumption Associated With Breast Cancer Risk

​Drinking the three glasses of milk per day recommended by US Dietary Guidelines is associated with a risk of breast cancer that is increased by as much as 80%, according to results of a large observational study recently published in the International Journal of Epidemiology."Consuming as little as 1/4 to 1/3 cup of dairy milk per day was associated with an increased risk of breast cancer of 30%," commented Gary E. Fraser, MBChB, PhD, Professor of Public Health, Medicine, and Preventive Medicin...
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