Low-grade prostate cancers have a much lower risk of cancer-specific death, while high-grade prostate cancers account for the majority of deaths from prostate cancer; therefore, precise diagnosis is of utmost importance. In order to achieve a high rate of accurate detection of this disease, standard biopsy in conjunction with magnetic resonance imaging (MRI) is necessary. A recent study found that when used together, these two techniques are more effective in targeting and sampling suspicious pr...
Men with metastatic castration-sensitive prostate cancer (CSPC) generally experience an initial response to androgen deprivation therapy (ADT), but with time, the cancer invariably becomes castration resistant. A new analysis of data from the phase 3 CHAARTED trial, published last week in JAMA Oncology, shows that men with low-volume metastatic CSPC who have the adrenal-permissive genotype of the HSD3B1 gene experience more rapid progression to castration-resistant disease and shorter overall su...
In metastatic castration-sensitive prostate cancer, both progression to castration-resistant disease and overall survival are negatively impacted by the adrenal-permissive genotype of HSD3B1, according to a new analysis of data from the phase 3 CHAARTED trial.Androgen deprivation therapy (ADT) almost always produces an initial response in metastatic prostate cancer; over time, however, the cancer inevitably develops a resistance to castration. One major way in which this happens is when the tum...
In the past decade, much progress has been made in the management of castration-resistant prostate cancer (CRPC), with numerous new agents improving outcomes in patients with this disease. However, many challenges still remain. In this interview with i3 Health, Judd W. Moul, MD, FACS, Professor of Urologic Surgery at the Duke School of Medicine, discusses strategies that community oncologists and urologists can utilize to determine the best treatment for their patients. He also discusses the rol...
At the 67th Society of Government Service Urologists (SGSU) Kimbrough Urological Seminar, held from January 15th to 19th, 2020, in Charlotte, North Carolina, i3 Health conducted a survey of participants regarding the formats in which they wished to receive continuing medical education (CME). Thirty-six individuals completed the survey, of whom 35 (97.2%) were physicians and other prescribers of medication. Results showed that despite the ever-increasing ubiquity of technology in our society, uro...