​Connecting With Patients With Cancer in Spite of COVID-19: Kiri A. Cook, MD

The stress of having cancer and the physical and financial toll of treatment can be difficult for patients, even under normal circumstances. During the COVID-19 pandemic, patients face additional stressors, including not only the fear of mortality from COVID-19 but also the emotional impact of isolation. This sense of isolation can be present even in patients' cancer care, as many appointments take place through videoconferencing and telephone calls; even when in-person appointmen...
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IVC Filter Efficacy in Patients With Cancer and Deep Vein Thrombosis: Rahul A. Sheth, MD

Patients with cancer are at substantially increased risk for deep vein thrombosis (DVT) and resulting pulmonary embolism. Together, these two forms of venous thromboembolism constitute the second leading cause of death for patients with known malignancies. The standard of care for DVT is anticoagulation, yet many patients with cancer and DVT are unable to receive anticoagulation because of the bleeding risk that it poses. In a study recently published in JAMA Internal Medicine, a team of investi...
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In Cancer Patients With DVT, IVC Filter Reduces Pulmonary Embolism Risk

A new study finds that for patients with cancer and deep vein thrombosis (DVT), placement of an inferior vena cava (IVC) filter reduces the risk of pulmonary embolism. Venous thromboembolism (VTE) poses a substantial problem for patients with cancer: it occurs four to seven times more frequently in this population, and it is the second overall leading cause of death for patients with known malignancies. Pulmonary embolism is a potentially deadly condition that can develop as a result of VTE, and...
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Preventing Venous Thromboembolism: Apixaban More Effective With Solid Tumors

A preplanned post-hoc analysis of the AVERT trial, a randomized, placebo-controlled, double-blind clinical trial of apixaban for the prevention of venous thromboembolism (VTE), reveals that among ambulatory patients with cancer initiating chemotherapy, characteristics of both the patient and the cancer in question impact the efficacy of apixaban for VTE prophylaxis. "Patients with active cancer have an increased risk of venous thromboembolism (VTE) complications which is associated with morbidit...
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Venous Thromboembolism Recurrence in Patients With Cancer

In patients with cancer who develop venous thromboembolism (VTE), cancer type plays a significant role in the risk of VTE recurrence after anticoagulation. A condition involving the formation of a blood clot that starts in a vein, VTE can negatively impact the clinical outcomes of patients undergoing cancer treatment. While anticoagulation therapies, including apixaban and rivaroxaban, are mainstays of treatment, patients with cancer experience higher rates of anticoagulation failure and bleedin...
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