Pediatric Brain Tumors: Cognitive Effects in Adulthood

Children with central nervous system (CNS) tumors have good prognoses; 75% will live at least five years after diagnosis. Unfortunately, a recent study has shown that these survivors experience neuropsychological problems and lower socioeconomic status later in life compared with their healthy peers.For this study, published in Cancer, the researchers analyzed data on 181 adult survivors of pediatric low-grade gliomas from the Childhood Cancer Survivor Study and compared them with a group of 105...
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New Therapeutic Target in Glioblastoma: FGL2

‚ÄčIn an immune regulatory protein that promotes the progression of glioblastoma multiforme (GBM) by suppressing the immune system, researchers at the University of Texas MD Anderson Cancer Center have found a potential therapeutic target.Until now, little research has been done about the role of immune-associated genes in the progression of brain tumors. "Classical wisdom is that brain tumor progression is linked to oncogene activation and tumor suppressor gene inactivation; however, genetic and ...
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