Breast Cancer Survivors Face Increased Cardiovascular Risks

Compared with those without cancer, older patients with breast cancer have a higher risk of developing cardiovascular disease, according to a study now published in the Journal of the National Comprehensive Cancer Network. "In older women diagnosed with breast cancer, there is now a greater likelihood of dying of diseases other than the cancer itself," write the investigators, led by first author Anthony Matthews, PhD, a postdoctoral researcher at the Karolinska Institute in Sweden. "Cardiovascu...
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Physical Activity Can Decrease Cardiovascular Risk in Childhood Cancer Survivors

In those who have survived childhood cancer, an unhealthy lifestyle can compound the risk of cardiovascular disease that can result from intensive cancer therapies. High blood pressure, high waist circumference, and high blood lipids, all of which are commonly found in childhood cancer survivors, can increase the chance of developing cardiovascular disease. However, according to a recent study, childhood cancer survivors could potentially mitigate the risk of cardiovascular disease with physical...
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Microvascular Endothelial Dysfunction Predicts Solid Tumor Cancer Risk

Microvascular endothelial dysfunction (MED), which is characterized by damage to the walls of small arteries in the heart, limiting the regulation of oxygen and blood supply, serves as an effective predictor of cardiovascular disease. In addition, a recent study reports, MED significantly increases an individual's risk of developing solid-tumor cancer. In a study now published in the European Journal of Preventive Cardiology, Amir Lerman, MD, the Director of Cardiovascular Research at Mayo Clini...
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Cancer Causes More Deaths Than CVD in High-Income Countries

Globally, cardiovascular disease (CVD) is the majority cause of death in those aged 35 to 70 years; however, according to a new study, in high-income countries, cancer mortalities are more common than death from CVD. The Prospective Urban Rural Epidemiology (PURE) study, results of which were published in The Lancet, involved 162,534 participants aged 35 to 70 years old from 21 countries across five continents, including low-income countries (LICs), middle-income countries (MICs), and high-incom...
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The Mortality Risk of Androgen Inhibitors for Prostate Cancer and Heart Disease: An Interview With Grace Lu-Yao, PhD, MPH

Abiraterone acetate and enzalutamide are oral androgen signaling inhibitor therapies used in the treatment of patients with advanced prostate cancer. However, because elderly patients with prostate cancer who also have cardiovascular disease are often excluded from clinical trials, little has been known about the effect of these therapies on the clinical outcomes of these patients. In this interview with i3 Health, Grace Lu-Yao, PhD, MPH, discusses the increased mortality and hospitalization ris...
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