Many older patients with breast cancer have significant comorbidities, increasing the challenges of treatment. These challenges are compounded by the fact that elderly patients with multiple comorbidities are frequently excluded from participating in clinical trials, resulting in a lack of treatment data for this population. Nina Tamirisa, MD, and colleagues recently published a study in JAMA Oncology reporting that in older patients with multiple comorbidities and estrogen receptor–positive, no...

In older patients with multiple comorbidities and estrogen receptor (ER)-positive, node-positive breast cancer, chemotherapy improves survival, according to a study published today in JAMA Oncology. "Breast cancer risk and the incidence of comorbidities increase with age. Treatment of elderly patients with significant comorbidities is challenging," write the investigators, led by first author Nina Tamirisa, MD, Assistant Professor of Breast Surgical Oncology at The University of Texas MD Anderso...