How Genetic Testing Results Impact Breast Cancer Treatment: Allison Kurian, MD, MSc

​With our ever-growing understanding of mutations that increase cancer risk and the rise of targeted treatments such as poly (ADP-ribose) polymerase (PARP) inhibitors that are indicated for specific mutations, the use of germline genetic testing for patients with breast cancer has increased significantly in recent years. How are these test results affecting patients' treatment? In a population-based cohort study published recently published in JAMA Oncology, Allison W. Kurian, MD, MSc, and colle...
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The Effect of Germline Mutations on Breast Cancer Treatment

Patients with breast cancer for whom germline genetic testing reveals pathogenic mutations often receive treatment that deviates from standard therapeutic guidelines, according to results of a population-based cohort study published today in JAMA Oncology. The use and importance of germline genetic testing for patients with cancer has increased in recent years as our understanding has grown regarding mutations that increase cancer susceptibility and as targeted treatments such as poly ADP ribose...
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