Antifungal Prophylaxis for Hematologic Malignancies: Yuan Wan, MD, PhD

While antifungal prophylaxis can effectively prevent invasive fungal infections in patients with hematologic diseases, there is no consensus on which prophylactic agents provide the greatest benefit for different patient populations. In a meta-analysis recently published in JAMA Network Open, a team of researchers found that among antifungal prophylactic agents, posaconazole may be the best option for patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS), while voriconazo...
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Antifungal Prophylaxis for Hematologic Malignancies: Which Agent Is Best?

In a meta-analysis evaluating the efficacy of prophylactic agents against invasive fungal infections (IFIs) for patients with hematological diseases, investigators found that posaconazole may be the best option for patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS), although voriconazole may be the best option for patients undergoing hematopoietic stem cell transplantation (HSCT). "Invasive fungal infections have emerged as important causes of morbidity and mortality i...
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How Cancer Type Affects COVID-19 Outcomes: Lennard Lee, DPhil, MRCP, BMBCh

While patients with cancer are at an increased risk of experiencing poor outcomes from COVID-19, there is significant variability in COVID-19 risk and mortality among patients with different tumor types and demographics such as age and sex, with those with hematologic malignancies facing the highest risk. In this interview with i3 Health, Lennard Lee, DPhil, MRCP, BMBCh, an Honorary Research Fellow at the University of Birmingham's Institute of Cancer and Genomic Sciences, discusses the signific...
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COVID-19 and Cancer: Tumor Type Affects Risk and Outcomes

Among patients with cancer, different tumor types and patient demographics are associated with varying COVID-19 risk and mortality, with patients with hematologic malignancies experiencing the highest susceptibility and poorest outcomes, according to a study recently published in The Lancet Oncology. Patients with cancer have been identified as a subgroup with increased susceptibility to SARS-CoV-2, the virus that causes COVID-19. "However, cancer encompasses many different diseases, with a dive...
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COVID-19 Outcomes in Patients With Cancer: Miao Liu, MD, PhD

Patients with cancer face unique challenges in the midst of the COVID-19 pandemic: not only do they have an increased risk of contracting COVID-19 in hospital settings, but they also experience more severe clinical outcomes from the disease compared with patients without cancer. In this interview with i3 Health, Miao Liu, MD, PhD, one of the investigators who recently reported these findings in Cancer Discovery, discusses the difficult challenges that patients with cancer face as they continue t...
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