Breast Cancer Survivors Face Increased Cardiovascular Risks

Compared with those without cancer, older patients with breast cancer have a higher risk of developing cardiovascular disease, according to a study now published in the Journal of the National Comprehensive Cancer Network. "In older women diagnosed with breast cancer, there is now a greater likelihood of dying of diseases other than the cancer itself," write the investigators, led by first author Anthony Matthews, PhD, a postdoctoral researcher at the Karolinska Institute in Sweden. "Cardiovascu...
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Overprescribing Preventive Drugs to Elderly Patients With Advanced Cancer

Researchers discovered that elderly patients with advanced cancer who continue to take some preventive drugs might not achieve clinical benefit during their remaining lifespan, thereby rendering the drugs unnecessary money and time wasters. In this study, published in Cancer, the investigators found that in 151,201 adults older than 65 with advanced cancer who passed away, patients were prescribed an average of 6.9 to 10.1 drugs over the last year of their life. Preventive drugs, such as antihyp...
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Class F Receptors: Potential Cancer Treatment Targets

Receptors located on the cell surface are heavily influenced by cancer mutations. According to researchers at the Karolinska Institute and Uppsala University in Sweden, Class Frizzled (Class F) of G protein-coupled receptors (GPCRs) could potentially be a therapeutic target. Hormones activate the receptors on cell membranes in order to start different cellular processes. G protein-coupled receptors, which comprise the most physiologically important membrane protein family, recognize a large vari...
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