Pembro/Pemetrexed-Platinum: How Does It Affect Patient QOL?

In patients with previously untreated, metastatic, non-squamous non-small cell lung cancer (NSCLC), pembrolizumab plus pemetrexed-platinum has proven to be an effective treatment compared with pemetrexed-platinum alone in increasing the proportion of patients who experience a complete or partial response, as shown in the KEYNOTE-189 study. Based on the results of this study, the FDA recently approved a new indication for pemetrexed in this combination for the first-line treatment ...
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The Deadly Consequences of Fine Particle Air Pollution

A new study finds an association between fine particulate matter (PM2.5) air pollution and deaths from nine different causes, including cardiovascular disease, cerebrovascular disease, hypertension, dementia, and lung cancer, among others. Furthermore, 99% of PM2.5-associated deaths were linked to levels of PM2.5 exposure currently deemed acceptable by US Environmental Protection Agency (EPA) recommendations.Atmospheric particulate matter with a diameter of less than 2.5 micrometers, PM2.5, is p...
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Racial, Age-Related Disparities in Lung Cancer Treatment

A new study reports that only 62.1% of US patients with lung cancer receive treatment that adheres to guidelines, and elderly and non-Hispanic black patients are disproportionately represented among those whose cancer is undertreated.For the study, now published in Annals of the American Thoracic Society, the researchers evaluated whether 441,812 lung cancer cases in the US National Cancer Database diagnosed between 2010 and 2014 received treatment that adhered to the National Comprehensive Canc...
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Yogurt and Fiber Intake May Reduce Lung Cancer Risk

Researchers have discovered that consuming more dietary fiber and yogurt decreases an individual's chance of developing lung cancer. Yogurt, a probiotic food, and dietary fiber, a huge source of prebiotics, offer many health benefits by modulating the gut microbiota and metabolic pathways."Our findings have no immediate clinical impacts on [patients with] lung cancer, but do have a major public health impact on lung cancer prevention," stated lead researcher, Xiao-Ou Shu, MD, PhD, Professor of M...
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Tumor Treating Fields Plus Chemo Effective for Mesothelioma

By delivering low-intensity alternating electric fields, Tumor Treating Fields (TTFields), a regional, antimitotic therapy, has been deemed effective in treating solid tumors. Researchers set out to discover if TTFields would be successful in combination with systemic chemotherapy for treatment-naive patients with unresectable malignant pleural mesothelioma.For this phase 2 study, published in The Lancet Oncology, the investigators enrolled 80 patients from 12 European academic and non-academic ...
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