CRISPR-Cas9 Technology Used to Understand Glioblastoma

The most common type of primary malignant brain tumor in adults, glioblastoma is also one of the deadliest cancers, with a median survival rate of 10 to 14 months. Until recently, understanding of glioblastoma growth and survival was limited. Now, scientists report that "reverse engineering" glioblastoma stem cells gene by gene using CRISPR-Cas9 unveiled multiple therapeutic targets to combat treatment resistance, including the SOX transcription factor family."We think that, in one big experimen...
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