Dasatinib Improves Outcomes in Patients With Chronic Myeloid Leukemia and High BMI

According to a subgroup analysis of a phase 3 study, dasatinib produces significantly faster and more durable responses compared with imatinib in patients with chronic phase chronic myeloid leukemia (CML) and a high body mass index (BMI). Previous studies have reported that patients with a high BMI, defined as over 25 kg/m2, are at an increased risk of not only developing CML but also of experiencing poorer outcomes when treated with first-line tyrosine kinase inhibitors (TKIs) such as imatinib....
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